Hi @djarin ,
Thanks for your interest in the NXP MIMXRT product, I would like to provide service for you.
Answer your questions:
1. Can I know what are the Factory default settings? will GPIO has higher priority than eFUSEs by default?
=>Answer: it is determined by your configuration.
If you don't do the fuse burn, then it will determined by the GPIO pin feature, this is the default situation.
As fuse burn can't be back, just can be from 0 to 1.
fuse default is all 0.
2. How GPIO can overridden eFUSEs? and what are the settings to be done to skip the GPIOs checks?
=>Answer: Not overridden eFuse, you can consider, if you burn the fuse, select boot from the fuse, then it will use the fuse configuration.
If you don't, then it will use GPIO.
Check this RM content, you will be more clear:

3. What does the "and/or" exactly mean in the diagram
=>Answer: some CFG can use the fuse bit even when you use the GPIO as the BOOT_CFG.
Eg, these fuse:

Also can be used with GPIO boot method.
Just the CFG fuse + BT_FUSE_SEL=1, and BOOT_MODE =00, will use the boot from fuse, and use fuse CFG related data.
Wish it helps you!
If you still have question about it, please kindly let me know.
If your question is solved, please help me to mark the correct answer, just to close this case.
Any new issues, welcome to create the new question post, thanks.
Best Regards,
Kerry