Hi @Gavin_Jia,
I use an MCU-link as a debugger interface. To manually load the signed application, I use a command like this:
LinkServer.exe flash MIMXRT1052xxxxB:IMXRT1050_Refill load C:\application_signed.bin --addr 0x60100000
I need to specify the flash command because I need to load this application onto a custom board that uses a different flash memory than the EVK board.
It work, the problem is that I don't know how to run this code automatically in the IDE. I tried a solution like this:

But it doesn't work; it seems that the command is completely ignored. I don't know how to check if the command reports an error when it is executed.
I tried various combinations of the command: I placed it in the initialization command section, in the run command section, and I tried the GDB version (like load data.bin.elf 0x70000). I attempted it with and without flash in front of it or on the previous line. Nothing changed; the load is never performed.

As a completion, the initialization command section included this command:
set non-stop on
set pagination off
set mi-async
set remotetimeout 60000
##target_extended_remote##
set mem inaccessible-by-default ${mem.access}
mon ondisconnect ${ondisconnect}
set arm force-mode thumb
${load}
Best regards.
Massimiliano