Hello Chris,
The PCA9450A crystal driver is not designed to accept an external clock signal like a MEMS oscillator. It is specifically a crystal oscillator driver, not a general-purpose clock input. It expects a passive crystal, not an active clock source.
The internal RC oscillator is typically less accurate and may drift more with temperature.
Yes, it helps save BOM cost and PCB space by integrating this clock into the PMIC itself.
BRs, Tomas