Hello [email protected],
So the easiest way (minimum of change to your model) would be to change the SPI settings from the SPI Config block. Set
frame size = 8
and enable
Continuous transfer
to get the following signal:

Let me explain why these settings: on one hand, you'll have transfer size set to 2 (due to usage of MUX block); on the other hand, you want to send 16bits. Given this context, you can only set the frame size to 8. After you have these settings, you only need to enable continuous transfer so that you don't have the CS go HIGH in the middle of the 2 bytes.
There are other ways for achieving the same end result, but being necessary to change more blocks in your model, I don't see it become relevant.
The easiest way in managing any kind of SPI transfer is by using 8bit frame size with cointinuous transfer enabled and making sure you give the SPI T'ransfer block an input of appropriate size (the transfer size you need).
Please let me know if you have other questions regarding this subject.
Kind regards,
Razvan.