Hello @Jain_Naman
For Power Configuration Options, if you have no special requirements, please use a single supply of 3.3V. If you have specific requirements, such as needing 1.8V power for a particular pin, you can consider adding two power supplies (1.8V and 3.3V).
I apologize, but I haven't found a specific document for MCXN546. You can Google to compare single supply and multi-supply configurations for more detailed information.
BR
Alice