Hi seanwu,
The LPCAC is disabled by default. For best performance, NXP recommends enabling it by clearing SYSCON->LPCAC_CTRL[DIS_LPCAC].
When enable LPCAC, Performance of code running in Flash or FlexSPI Flash matches RAM performance because of LPCAC
This AN includes LPCAC usage. Enable/DIsable LPCAC to test MCX performance.
https://docs.nxp.com/bundle/AN14139/page/topics/mcx_n-series_architecture_overview.html
MCXA153 reference manual also introduces the low power cache controller control method.

You could refer it to test your IO performance. For more about IO performance, please refer your other thread “MCXA153 GPIO rise/fall time performance”
Hope this helps,
Jun Zhang