Hello Stefan,
Recently NXP Apps team found the USB PHY will take higher current consumption in DSM mode, and it can't be turns off by SW. So, we suggest add external power switch (MOSFET) to turns off the VDD_USB_OTGx_3P3_IN in DSM mode.
(In case the USB OTG port is not using, you can connect VDD_USB_OTGx_3P3_IN and VDD_USB_OTGx_1P0_CAP
to GND to reduce the power consumption
The ADC port may take higher current consumption in DSM mode even it is not using
Turns off the Digital power rails (NVCC_xxx) in DSM mode is not allow, please keep the digital power rails on.
The second issue may cause by the NVCC_xxx power off, please check it again.
Best Regards,
Jaime