Hi Paul,
Using FlexIO you should be able to emulate complete UART functionality so you do need to worry about any negative impact on the UART operation. An advantage of FlexIO is that gives you the opportunity to increase UART modules available in the device as well as other protocols as you mentioned.
I recommend you to check our SDK examples we provide depending on the MCU you are working on. This will give you more hints regarding FlexIO functionality.
Welcome | MCUXpresso SDK Builder
I hope this helps!
Best regards,
Felipe
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