Hi @p_shep
Thank you so much for the clarification and for your patience.
Unfortunately, about what you are trying to do, there is no tricks to force it as far as we know, the only way that I think is to use the same I2C data line as an alternative in another pin, and enable the interrupts on another pin configured as GPIO, so it might disable I2C after an ISR occurs using some callback and then, you can re-enable I2C data line and toggle this GPIO, but you cannot connect this GPIO to I2C module, as they use different clock rates and different internal clocks feeders, so it is kind of impossible.
Hope it is helpful, thanks a lot again for your patience.
Best Regards.
Pablo Avalos.