Hello,
The device supports both protocols, there is even an example for USB and one for the Bluetooth Le functionality. It will depend on how much memory you will need with the devices as the Bluetooth LE protocol implementation that we have available needs space and the footprint depend on the example you use. You can check more about the footprint in the release notes in the documentation folder of the SDK that you can download form this link.
Also, please take into account that we do have those examples in separate file but there is an effort you need to do when combining both examples in one, as well as you will need to create your custom profile for the Bluetooth LE communication based in the FIDO alliance specification.