Hi@rlaxortn
In your last answer, you said "because MCU Supply voltage is 3.3V". Now you say "MCU VREFH is 5.0V". Are you serious?
In your configuration , the TempSense Voltage Supply is 0x53, that is 5.3V
the Adc Voltage Reference is 53->0x35->3.5V
We've been talking for so long and you keep making the same mistakes。
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If your VREFH is 5V, then you should set both values to 0x50.
Secondly, to improve stability, you can set the following parameters to a larger value and test again.
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