Hi,
technically, yes - since each module has its own mux and input stage, they can operate in parallel. However, if the analog signal is shared, the loading effects (e.g. input impedance, capacitance) could affect accuracy. If both modules try to sample at the same time, you might get inaccurate ADC readings or unstable comparator behavior. The analog mux and sampling circuitry might load the signal differently depending on which module is active.
So a best practices should be avoid simultaneous use of the same pin for both ADC and CMP unless absolutely necessary.
BR, Petr