Hi njk909,
The MCF52259 is combined MCU (has intergrated flash and sram) and MPU (support extermal memory devices like MRAM, SRAM, and NOR flash).
The MPU mode can boot from external devices like MRAM (as MartinK mentioned) and NOR flash but does not have the ability/capability to boot from USB or compact flash, or serial flash.
Hope this helps.
Regards,
David