Hi,
Below is the LPC5410x internal 12MHz IRC spec:

The IRC clock frequency drift with temperature is normal.
As you can see the full temperature range clock frequency accuracy within 3.5%.
The UART communication also allow communication clock accuracy tolerance, please check here for the detailed info.
I would recommend two ways to reduce the UART communication error rate:
1> reduce the UART communication baud rate;
2> using IRC Control register to trim the IRC with temperature change.
Wis it helps.
Have a great day,
Mike
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