Hi Ian Benton,
Thank you for your interest in NXP Semiconductor products and
Actually, I don't the exact reason which causes this phenomenon, as the ADC calibration process is unknown, however, in general, it needs many conditions must be stable during calibration, for example, ADC's clock source and frequency, power configuration, voltage reference selection, sample time, etc.
Hope it helps.
Have a great day,
TIC
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