As stated on Users's Manual (ADC chapter):
"The APB clock (PCLK) is divided by CLKDIV +1 to produce the clock for the ADC, which
should be less than or equal to 4.5 MHz. Typically, software should program the smallest
value in this field that yields a clock of 4.5 MHz or slightly less, but in certain cases (such
as a high-impedance analog source) a slower clock may be desirable."
The maximum PCLK is around 48 MHz (the exact value depends on your specific setup and clock source, PLL, interrnal RC oscillator,...).