If you're using it with Windows 8 or Windows 10, there is a known issue where it may get corrupted and the debug interface goes down. I've been wrestling with the same board, and while I was able to get the OpenSDA debug interface working again, I can't seem to get the mass storage interface working again. Partly because when I boot it in bootloader mode, the available space reported is smaller than available for the msd/debug application. This link may help. OpenSDA Serial and Debug Adapter|NXP
Is it showing signs of life at least? If you plug the USB cable into the SDAUSB connector and plug it into your computer, does the green light come on? If it's flashing, it may be stuck in bootloader mode and you should see a disk drive showing up in Windows that says "bootloader". If you download the OpenSDA drivers from Pemicro (you'll need to sign up), the DEBUG-FRDM-K64F_Pemicro_v108a_for_OpenSDA_v2.0.bin file at least seems to restore the debug interface and I can program and debug from McuXpresso.