I didn't even realize that the K22FN1M0 had 5V tolerant inputs. Huh. I'd imagine it'd probably be OK then. With an ESD protection diode tied to Vdd you'd get something like 310 uA at 3.1v injected into Vdd, I think. Without one, you're probably fine. I'm pretty sure I've had that condition on some MK22FN1M0AVLH boards without any trouble.
I say hook up the I/O pin to 3.3v without any current limiting. If something goes pop and smells bad, then your answer is no. If it's still working fine the next day, then I think a few hundred uA isn't going to hurt it.
Maybe someone from NXP can give you a more definitive answer, but I'm an empiricist. :smileywink:
Scott