Hello,
any special reasons why you are using 10.1, and not 10.2? I ask because 10.2 so much better and faster that I have put away my old 10.1 installation a while back. So I cannot try it right now with a 10.1 (until I have it installed).
But the debugger is looking for a memory configration file. It is usually inside your project the Project_Settings folder.
So for your device it is probably Project_Settings\Debugger\MC9S08QExx.mem.
The simplest would be if you create a new project with the wizard (File > New > Bareboard project) and then use this one as a reference. The link to the .mem file is made in the debug configurations. The place of the .mem file specified in the debugger is a little bit different for 10.1, but for 10.2 it is in the debug run configurations (menu Run > Configurations).
Attached is the screenshot of my 10.2.
Hope this helps,
BK