Hello Deepak_India
Good day!
- Can I use this Sensor to measure the above mentioned pressure range.?
Yes you can use it, 330 mmHg ≈ 44 kPa, so is under range
- Please tell me the connection of Vaccum port P2. Is this vacuum port P2 connected to Vacuum or vented to Atmospheric pressure?
I recommend you take a look to the datasheet
Chapter: 9.4 Pressure (P1) / Vacuum (P2) side identification
NXP designates the two sides of the pressure sensor as the Pressure (P1) side and the
Vacuum (P2) side. The Pressure (P1) side is the side containing silicone gel that isolates
the die from the environment. The NXP MPX pressure sensor is designed to operate with
positive differential pressure applied, P1 > P2.
- The output of this Sensor is differential. But no where in the datasheet, i could find the actual values of Vout+ and Vout- . Instead I understood that the output varies wrt 0.8mV/kPa sensitivity and could list out the Vout values wrt each kPa. But please explain with what formula this Vout is linked to Vout+ and Vout-
Okay the datasheet
The typical sensitivity is 0.8 mV/kPa when powered with 10 V.
The output voltage is given by:

For example, at 10 V supply:
At 0 kPa: Vout- = 0mV
At 50 kPa: Vout+ = 0.8×50 = 40mV
Vout = 40mV
The datasheet say:

In this way we can confirm that this would be the correct relationship between pressures
I hope this information has helped you, please let me know if you need help with anything else.
Have a great day and best of luck.