Hi Bernd,
If the binary is plain in the NAND or NOR flash, I think SE050 can help little on such kind of issue, instead a tamper detection device is needed for your case. As I know, some host controllers support tamper detection, for example, Kinetis K81,
Please kindly refer to Arm® Cortex®-M4|Kinetis K81 150 MHz 32-bit MCUs | NXP for details.
Hope that helps,
Have a great day,
Kan
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