Hello iaboelen,
I hope all is great with you. Thank you for using the NXP communities.
Could you please review the questions below for a better understanding?
Do you mean the I2C CRC verification?
When this feature is enabled, a selectable CRC verification is performed on each I2C transaction. Could you please confirm that it is enabled (OTP_I2C_CRC_EN = 1)?
Are you trying to perform an I2C secure write? When OTP_I2C_ SECURE_EN = 1, the secure write is enabled. I guess you are trying to write the secure registers.

Regards,
David