For some unused pins please follow below suggestions setting:
Customer can leave CLKOUT and TS1-4 pins open when not using them in application.
Customer can set CLKOUT pin to be in high-Z mode by setting CLKOUT_ctl register (13h) bit[2:0] = 111b. And set TS1-4 pin are to be inactive pins by setting Control_4 register (03h) bit [7:4] = 0000b and Control_5 register (04h) but [7:4] = 0000b.