Thank you for contacting NXP Technical support.
Following your inquiry, MCF5280CVM66J is an obsolete product.
As we delete all the information related to obsolete products, we do not have the option to validate the meaning of the last letter.
Usually, makes reference to packing type, but as we do not longer have documentation that validates, we can not confirm this.
I apologize for the inconvenience this may cause you.
Regards,
Susi