Hi hjhjhj,
It might be - but all depends on the type of applications.
In general when i'm thinking about a calibration - i'm thinking of a sort of routine that is executed one at system startup.
If that is the case for your application then, Simulink can help you. There is a way to call a routine during the Simulink initialization routine. Inside this routine you can call your calibration function that might implemented the automatic calibration.
There is a topic that covers this in great details that was opened by edenli here:
About Code generation in the Model Based Software
Resolver Initialization - Code Generation and Optimization in the Model Based Software
The other alternative, if your calibration is about the user interacting with the application to calibrate manually some parameters is to use the Freemaster, perform the tunning/calibration with the system running on the MCU and the save manually those parameter in the final application (hard-coding)
So, it depends on your setup and type of application. Bottom line is even if the toolbox might not have support out of the box for all the functionalities that you might need, since it is based on Simulink you can easily extend its capabilities by deploying Matlab functions.
Hope it helps!
Let us know how you'll be tackling this challenge.
Thank you!
Daniel