Hi Shiv Agarwal,
Thank for you for your interest in NXP Semiconductor product and for the opportunity to serve you.
According to the figure you shared, it suggests you restart your debug session. If the problem recurs, then power cycle your debug probe and restart debugging, whether you already had tried these tricks.
In my opinion, I'd highly recommend you to check the hardware at firstly, especially for the debug interface design, I was wondering if you can share the schematic.
To validate debug interface design, connect it with the Jlink debugger, then open the J-link commander to check whether the LPC54618 be able to be identified.

Have a great day,
TIC
-------------------------------------------------------------------------------
Note:
- If this post answers your question, please click the "Mark Correct" button. Thank you!
- We are following threads for 7 weeks after the last post, later replies are ignored
Please open a new thread and refer to the closed one, if you have a related question at a later point in time.
-------------------------------------------------------------------------------