Hello Vu,
So after cutting several traces on the PCB to isolate the core of the problem. It turns out the problem is caused by an EMI filter with ESD chip p/n AOZ8040DI. The transmit line, pin15 is connected to one channel of the EMI filter with ESD chip and after removing the signal from the chip the problem disappears. The chip shouldn't caused any problem, but I will fully investigate the problem at later time but for now it solves my problem.
It would seem that you are using an unsuitable protective device. It appears that the device you are using is a uni-directional type, able to accept voltage excursions in the positive direction only For RS232 operation, the output driver gives both positive and negative voltage excursions. The protective device is therefore clamping the negative output to a level of about -0.7 volts. This represents an overload condition, that will reduce of the V- voltage level from the charge pump, sufficiently so that the READY signal remains inactive.
The solution would be to use an alteratate bi-directional protective device that provides high-Z for both positive and negative voltage excursions.
Regards,
Mac