Hi
With lpcopen msc demo code, I can't reproduce your issue. So the problem is not on LPC part.
Your USB can't connect 8GB or 4GB msc, and you use custom board and SW, thus there may be many possiabilities, the card, the SW, HW design.
I suggest you testing lpcopen msc demo code on your board first to isolation where is the problem.
Thanks,
Jun Zhang