Hi Jaime
The D+/D- pull downs are required in USB-OTG / HOST modes (the outputs are used to control pull-downs in the range 14.25k and 24.8k, which should be either active or high impedance depending on the mode).
If you are using only device mode you don't need them and it is probably best to remove the resistors to the CS outputs to ensure that there is no disturbance.Generally these signals are static and so could probably be realized with normal ports.
However I don't have concrete experience with OTG mode so there may be an exception somewhere. Possibly some one else could confirm or explain consequences.
Regards
Mark
www.uTasker.com