Hello,
It ain't necessarily so! It depends on the specific application.
In many instances, the extra resolution that 12-bit mode provides is an advantage, where small changes need to be detected, and where the absolute calibration is less important. Digitization of speech comes to mind - the dynamic range would be increased by 12dB compared with 10-bit mode.
For other applications, a calibration process can compensate for some of the measurement errors (such as zero scale error and full scale error), and 12-bit mode will then give more accurate results than 10-bit mode because of the increased resolution.
Regards,
Mac