The specifications for the device show characteristics for the P1>P2 configuration only. I was hoping to utilize the device in the P2>P1 configuration as that would suit our implementation better. Is there any reason to believe that the characteristics of the device in the P2>P1 configuration would be appreciably different?
Most of the NXP pressure sensors including the MP3V5050GC6U are based on a silicon diaphragm and cannot tolerate a pressure that alternates from positive to negative or having pressure on port P2 higher than pressure on Port P1 without resulting damage.
However, there is a family of pressure sensor from the NXP portfolio designed to measure both, positive and negative pressure within the same system, this family is the MPXV70xx family pressure sensors. We currently have 3 different sensors from this family, very similar between them but with different pressure range:
+ MPXV7002 – Pressure range from -2 to +2kPa: https://www.nxp.com/docs/en/data-sheet/MPXV7002.pdf
+ MPXV7007 - Pressure range from -7 to +7kPa: https://www.nxp.com/docs/en/data-sheet/MPXV7007.pdf
+ MPXV7025 - Pressure range from -25 to +25kPa: https://www.nxp.com/docs/en/data-sheet/MPXV7025.pdf
The MPXV7025DP have an operational range of 50kPa (same as the MP3V5050GC6U), but instead of measure from 0 to 50kPa, it measure from -25 to +25kPa.
It is mentioned that this sensor is supply with 5V, but you can use it at 3V as the MP3V5050 because the sensor output is ratiometric, this means that output voltage of the sensor is directly affected by the supply voltage. You can supply it with 3V and should not affect the sensors functionality.