Hello @vk5
Hope you are doing well.
As you mention, write endurance depends on the temperature and can be lower if the device operates under limit conditions.
Write endurance would depend on the WRITE command functionality. NFC WRITE command requires a page address and writes 4 bytes of data into the addressed page. I2C WRITE operation always handle 16 bytes (one block) to be written.
For operations requiring several memory transactions, please consider using the SRAM.
Regards,
Eduardo.