Safety Manual for MPC5746R, Rev. 2.1, 07/2017, section 2.1.3 Mission Profile specifies a max Trip time (driving cycle, Ttrip) of 12 hrs. I have an application using MPC5746R with significantly longer mission profile with a requirement for no power-on reset during operation. Is there a way to extended T_trip? What will be the consequences if I operate for extended time periods? Will the safety case become invalid after 12 hrs?
The safety manual is targeted to achieve ASIL-D safety class and still it is only recommendation. There are lot of ways how to achieve ASIL-D and safety manual is offering just one of them.
Since you do not share your safety target or industry, you should follow requirements for your safety certifications and not stick with safety manual ones.
If you are not sure, then just consult with your safety engineer or certification company.