Hi Dave S,
Thank you for your interest in NXP Semiconductor products and for the opportunity to serve you.
Whether you mean that MCU wouldn't response 'Synchronized ' to '?' in 150 mS after forcing the LPC4074 to enter UART ISP mode, however, it can recover response ability when exceeds 200 mS.
If yes, I'd like to say this non-response time is not the delay time, during this time, ROM bootload initializes the clock, peripheral, etc.
So please wait for a while before sending '?', just keep in mind.
Hope this is clear.
Have a great day,
TIC
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