Hi,
First of all, pls test if the ADC result is correct.
1)connect the ADC_1 to GND directly, then check if the sample approaches to zero
2)connect the ADC_1 to GND, then check if the sample approaches to 0xFFF
If the above two tests are okay, but your actual application test has issue, I suppose that your external signal conditional has issue. In detail, the 270kohm resistor is too large, This is my suggestion, you can remove the 200 ohm resistor and replace with a buffer based on AMP, then use ADC to have a test for the AMP output.
The ADC input impedance is small.
Hope it can help you
BR
XiangJun rong