Hi Koichi Sakagami,
According to reference manual, the USB regulator should be put into STANDBY mode when the chip is in Stop mode.
When the MCU is not powered by the VDD which is almost equal to the MCU enters the low power mode.
So I'd highly recommend that you should eliminate the put the USB cable to a USB host while the MCU is not powered.
Have a great day,
Ping
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